We propose Discrete Diffusion Bridges (DDB), a novel framework designed to resolve the fundamental spatiotemporal misalignment of standard discrete diffusion in image translation and generation. By corrupting data into a pure mask state via a random schedule, the conventional forward process induces a twofold misalignment: spatially, this pure-mask destination entirely discards the rich structural priors of the source image; temporally, the random masking order inherently contradicts the ``easy-first, hard-last'' decoding mechanism used during inference. To address this, DDB constructs a direct and efficient trajectory between domains. Spatially, we introduce a hybrid absorption mechanism that redefines the absorbing state to a stochastic mixture of mask and source tokens, effectively injecting source prior as spatial anchors into the latent space. Temporally, we design an information-guided noise schedule that quantifies semantic variation to prioritize the corruption of high-information regions at earlier timesteps. This ensures the model learns to resolve difficult semantic changes using robust context from invariant regions. Extensive experiments validate the versatility and robustness of our framework across diverse generative paradigms. DDB effectively balances edit alignment with structural fidelity across both text-guided semantic manipulation and pure structural image translation, while inherently complementing text-to-image generation and guaranteeing robust high-quality decoding under extremely low sampling steps. Code and models are available at \href{https://github.com/HKU-HealthAI/DDB}{https://github.com/HKU-HealthAI/DDB}.

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