Modern autonomous vehicles are equipped with multiple sensors, such as cameras, LiDAR, and radar, for comprehensive environmental perception. However, robust cross-modal feature fusion remains a critical challenge, as the reliability of each sensor varies significantly across diverse real-world driving conditions, including poor visibility and adverse weather. While uncertainty quantification (UQ) mitigates this issue by allowing models to prioritize reliable signals, existing uncertainty-aware fusion methods typically rely on simple feature-level uncertainty estimates and thus often fail to generalize effectively in complex, out-of-distribution scenarios. To address this limitation, we propose CRUISE, a novel uncertainty-aware cross-modal sensor fusion framework. CRUISE integrates a vision-language model (VLM)-guided UQ module that generates fine-grained, pixel-level uncertainty estimates. By leveraging the VLM's rich prior knowledge and superior contextual reasoning, our approach provides a highly informative guide for the fusion process. Furthermore, we introduce a dynamic adaptive mechanism that explicitly models and captures cross-modal dependencies, ensuring the framework fully exploits the inherent complementary nature of multi-sensor inputs.

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