Nanodevices with Terahertz (THz)-based wireless communication capabilities are providing a primer for flow-guided localization within the human bloodstreams. Such localization is allowing for assigning the locations of sensed events with the events themselves, providing benefits in precision medicine along the lines of early and precise diagnostics, and reduced costs and invasiveness. Flow-guided localization is still in a rudimentary phase, with only a handful of works targeting the problem. Nonetheless, the performance assessments of the proposed solutions are already carried out in a non-standardized way, usually along a single performance metric, and ignoring various aspects that are relevant at such a scale (e.g., nanodevices' limited energy) and for such a challenging environment (e.g., extreme attenuation of in-body THz propagation). As such, these assessments feature low levels of realism and cannot be compared in an objective way. Toward addressing this issue, we account for the environmental and scale-related peculiarities of the scenario and assess the performance of two state-of-the-art flow-guided localization approaches along a set of heterogeneous performance metrics such as the accuracy and reliability of localization.

翻译：具备太赫兹无线通信能力的纳米器件为人体血流内的流引导定位提供了基础。此类定位能够将感知事件的位置与事件本身关联起来，在精准医疗领域带来诸多益处，例如实现早期精确诊断，同时降低成本和侵入性。流引导定位仍处于初级阶段，目前仅有少数研究针对该问题展开。然而，现有解决方案的性能评估仍以非标准化方式进行，通常仅采用单一性能指标，且忽略了在此尺度（如纳米器件有限能量）和此类挑战性环境（如体内太赫兹传播的极端衰减）下相关的多种因素。因此，现有评估方法的现实性较低，且无法进行客观比较。为解决这一问题，我们综合考虑了该场景中环境与尺度相关的特殊性，并基于一组异构性能指标（如定位精度与可靠性）评估了两种先进流引导定位方法的性能。