We present a biologically detailed extension of the classical Hopfield/Marr auto-associative memory model for CA3, implementing ten populations (two asymmetric pyramidal subtypes, eight GABAergic interneuron classes), forty-seven compartments, multi-rule plasticity (recurrent Hebb, BCM anti-saturation, mossy-fiber short-term, endocannabinoid iLTD, burst-gated Hebb), and a bimodal cholinergic encoding/consolidation cycle. Evaluated on pattern completion across auto-associative, associative, and temporal regimes, and on a controlled inhibitory-proportion manipulation at $N{=}256$, the full architecture exhibits \emph{three qualitative signatures absent from a minimal Hopfield baseline}: (i)~multi-attractor cross-seed behaviour at $K{=}5$ with biologically realistic inhibitory proportions, where two of five seeds converge to positive attractors with margin ${+}0.10{-}0.22$ (Cohen's $d{=}0.71$, one-sided $p{=}0.08$); (ii)~target-selective associative recall in paired $(A, B)$ memory at $K{\geq}5$, where the full model retrieves $B$ from a partial cue of $A$ while the minimal model echoes $A$ (Pearson margin $Δ{=}{+}0.163$ at $K{=}5$); (iii)~reduced cross-seed variance of the full model below the minimal baseline under clean upstream, with ratios $1.0{-}3.0$. These three signatures are architecture-specific: they appear consistently across independent regimes and are absent from the minimal control.

翻译：我们提出了经典Hopfield/Marr CA3自联想记忆模型的一个生物详细扩展，实现了十个群体（两种非对称锥体亚型、八类GABA能中间神经元）、四十七个隔室、多规则可塑性（循环Hebb、BCM抗饱和、苔藓纤维短时程、内源性大麻素iLTD、爆发门控Hebb）以及双峰胆碱能编码/巩固周期。在自联想、联想和时序模式下的模式完成任务中评估，并在$N{=}256$下进行受控抑制比例操作，完整架构展现出三种在最小Hopfield基线中缺失的定性特征：（i）在$K{=}5$且具有生物真实抑制比例时的多吸引子交叉种子行为，其中五个种子中的两个收敛至正吸引子，边际为${+}0.10{-}0.22$（Cohen's $d{=}0.71$，单侧$p{=}0.08$）；（ii）在$K{\geq}5$的配对$(A, B)$记忆中的目标选择性联想回忆，其中完整模型从$A$的部分线索中检索出$B$，而最小模型回放$A$（在$K{=}5$时Pearson边际$Δ{=}{+}0.163$）；（iii）在上游清洁条件下，完整模型的交叉种子方差低于最小基线，比值范围为$1.0{-}3.0$。这三种特征具有架构特异性：它们在独立机制中一致出现，且在最小控制中缺失。