Large-scale egocentric human videos provide rich and scalable manipulation experience for robot policy learning, yet substantial embodiment gaps in visual appearance, kinematic structure, and action spaces hinder effective knowledge transfer. Existing methods often decouple cross-embodiment knowledge alignment from robot policy learning, making it difficult for human manipulation knowledge to directly and fully contribute to robot action learning. To address this issue, we propose Nexus-VLA, a hybrid policy learning framework that enables cross-embodiment knowledge transfer through end-to-end human-robot joint training, allowing human manipulation experience to directly contribute to robot policy learning. We first introduce a hierarchical cross-embodiment semantic alignment paradigm that progressively establishes shared manipulation semantics from task intent to fine-grained interactions, enabling more complete use of the manipulation knowledge contained in human videos. Building on this hierarchy, we design a shared manipulation latent representation that jointly encodes multi-level shared knowledge into an internal representation directly used for continuous action generation, improving policy learning efficiency while effectively leveraging human knowledge. Across RoboCasa-GR1, OOD settings, and real-world robot experiments, Nexus-VLA achieves an 80.5% task success rate on RoboCasa-GR1 and demonstrates strong advantages in human-data utilization, learning efficiency, and cross-scenario generalization.

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