Reference-based event-to-video reconstruction aims to recover target RGB frames from a reference frame and the event stream captured over the reference-to-target interval. Although events provide fine-grained temporal cues, they encode sparse and asynchronous log-intensity changes rather than absolute appearance, making faithful reconstruction intrinsically challenging. The central challenge lies in associating event-derived target-time structures with relevant appearance information from the reference frame, especially under complex motion and long temporal intervals. In this work, we propose Engram-E2VID, a structure-guided framework that reconstructs target frames through the generative activation of appearance engrams. Specifically, the reference frame is encoded into token-space appearance engrams, while the event stream and reference context are transformed into a target-time motion-structure scaffold that captures motion boundaries and event-induced structural changes. Within a one-step diffusion backbone, scaffold-derived structural tokens progressively interact with and activate relevant appearance engrams across layers. This token-space association allows target structures to access reference appearance without relying on direct pixel-wise correspondence, while the diffusion prior complements uncertain or newly revealed regions. Across three benchmarks, Engram-E2VID improves PSNR by up to 3.29 dB and reduces LPIPS by up to 0.08 over the strongest same-input baseline, while degrading more slowly as the reconstruction interval increases.

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