We consider a \emph{family} $(P_\omega)_{\omega \in \Omega}$ of elliptic second order differential operators on a domain $U_0 \subset \mathbb{R}^m$ whose coefficients depend on the space variable $x \in U_0$ and on $\omega \in \Omega,$ a probability space. We allow the coefficients $a_{ij}$ of $P_\omega$ to have jumps over a fixed interface $\Gamma \subset U_0$ (independent of $\omega \in \Omega$). We obtain polynomial in the norms of the coefficients estimates on the norm of the solution $u_\omega$ to the equation $P_\omega u_\omega = f$ with transmission and mixed boundary conditions (we consider ``sign-changing'' problems as well). In particular, we show that, if $f$ and the coefficients $a_{ij}$ are smooth enough and follow a log-normal-type distribution, then the map $\Omega \ni \omega \to \|u_\omega\|_{H^{k+1}(U_0)}$ is in $L^p(\Omega)$, for all $1 \le p < \infty$. The same is true for the norms of the inverses of the resulting operators. We expect our estimates to be useful in Uncertainty Quantification.

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