Causal mediation analysis of cluster-randomized trials can reveal how interventions affect outcomes through individual and spillover pathways. Most existing methods target natural mediation effects under assumptions that exclude treatment-induced mediator--outcome confounding. We develop a semiparametric framework for interventional mediation effects that accommodates such confounding and within-cluster interference without requiring cross-world independence assumptions. We identify cluster-average and individual-average direct and indirect effects and decompose the indirect effect into individual and spillover components, distinguishing pathways through an individual's own mediator and those of other cluster members. These contrasts evaluate hypothetical interventions on the joint mediator distribution and can differ from treatment effects carried through individual causal pathways represented by natural effects, thereby providing an intervention-oriented perspective that complements natural effects. We derive efficient influence functions to construct estimators using cluster-level cross-fitting, characterize their multiple-robustness properties, and establish conditions for asymptotic normality and semiparametric efficiency. To facilitate implementation, we develop a lower-dimensional reparameterization that reduces the need for multivariate density estimation and integration and allows nuisance functions to be estimated using parametric models or machine learning. Simulation studies evaluate finite-sample performance, and an application to a cluster-randomized trial of cognitive behavioral therapy for chronic pain illustrates the proposed methods.

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