The design of microfluidic devices is a cumbersome and tedious process that can be significantly improved by simulation. Methods based on Computational Fluid Dynamics (CFD) are considered state-of-the-art but require extensive compute time-oftentimes limiting the size of microfluidic devices that can be simulated. Simulation methods that abstract the underlying physics on a higher level generally provide results instantly, but the fidelity of these methods is usually worse. In this work, a simulation method that accelerates CFD simulations by exploiting simulation methods on higher levels of abstraction is proposed. Case studies confirm that the proposed method accelerates CFD simulations by multiple factors (often several orders of magnitude) while maintaining the fidelity of CFD simulations.

翻译：微流体装置的设计是一个繁琐且耗时的过程，而仿真可以显著改善这一状况。基于计算流体动力学（CFD）的方法被认为是当前最先进的技术，但需要大量的计算时间——这通常限制了可仿真的微流体装置尺寸。在更高抽象层次上对底层物理进行简化的仿真方法通常能即时提供结果，但这些方法的保真度通常较差。本文提出了一种利用更高抽象层次仿真方法加速CFD仿真的技术。案例研究表明，所提出的方法在保持CFD仿真保真度的同时，可将仿真速度提升数倍（通常可达几个数量级）。